MetaHD: A Multivariate Meta-Analysis Model for Metabolomics Data

Performs multivariate meta-analysis for high-dimensional metabolomics data for integrating and collectively analysing individual-level metabolomics data generated from multiple studies as well as for combining summary estimates. This approach accounts for correlation between metabolites, considers variability within and between studies, handles missing values and uses shrinkage estimation to allow for high dimensionality. A detailed vignette with example datasets and code to prepare data and analyses are available on <>.

Version: 0.1.1
Depends: R (≥ 3.5.0)
Imports: dplyr, tidyr, metafor, corpcor, Matrix, matrixcalc, Rcpp (≥ 1.0.0)
LinkingTo: Rcpp, RcppArmadillo
Published: 2024-06-25
DOI: 10.32614/CRAN.package.MetaHD
Author: Jayamini Liyanage [aut, cre], Alysha De Livera [aut]
Maintainer: Jayamini Liyanage <j.liyanage at>
License: GPL-3
NeedsCompilation: yes
CRAN checks: MetaHD results


Reference manual: MetaHD.pdf


Package source: MetaHD_0.1.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): MetaHD_0.1.1.tgz, r-oldrel (arm64): MetaHD_0.1.1.tgz, r-release (x86_64): MetaHD_0.1.1.tgz, r-oldrel (x86_64): MetaHD_0.1.1.tgz
Old sources: MetaHD archive


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